Despite the non-finishes, Domenicali says pace rather than reliability is the main issue for Ferrari.
"Reliability was one big issue, but I have to be fair and honest - the results of today's race were decided by a lack of performance," he said.
"With Felipe, retrospectively, we were wrong with the strategy – it was maybe too aggressive and that was pretty clear. With Kimi it was okay in terms of strategy. So we have to put all the things in the proper list of priority.
"We saw Brawn is really very, very fast, strong and consistent. In normal circumstances, without any safety car, they would fly away. So if we have to target, that is our target."
Domenicali believes that Brawn GP has reaped the rewards from starting work on its 2009 car earlier than its rivals, but the Italian says the different characteristics of the Sepang circuit could help Ferrari to improve in Malaysia next weekend.
"There is a lot of work to do, this is natural, because on this side the fact that you [Brawn] are able to have more time to spend on a new project gives you results.
"For sure they were better than us, so just to understand maybe better the situation next weekend where we will be at a different track, at a track like Malaysia with a different grip situation. One element of important understanding is the tyres. The usage is also connected to the KERS, so there is a lot of things we need to understand in these days about that."